.Attributes Medication, Published online: 18 September 2024 doi:10.1038/ s41591-024-03300-3Genomic and epidemiologic analyses revealed that an unfamiliar reassortant virus-like lineage of the Oropouche virus, which has actually been distributing in the western side Amazon.com location of South america for about a many years, is actually associated with the recent human outbreaks between 2022 and 2024.